Naxitamab 新
仅供科学研究,不可用于个人用途。
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中文名称 | 那昔妥单抗 |
英文名称 | Naxitamab |
中文别名 | HU3F8;Humanized 3F8 |
英文别名 | HU3F8;Humanized 3F8 |
CAS号 | 1879925-92-4 |
产品编号 | BCP46215 |
纯度 | 98% |
分子量 | |
分子式 | |
储存条件 | Store at 4-8°C |
配送 | 惯例下常温包邮(中国大陆地区) |
Naxitamab (hu3F8) is a humanized monoclonal antibody that targets ganglioside GD2 that was developed by Y-mAbs Therapeutics for potential to treat high risk neuroblastoma. GD2 is a sialised glycosphingolipid cell adhesion molecule, that is highly expressed on neuroectoderm-derived tumours and sarcomas, including neuroblastoma, retinoblastoma, melanoma and small cell lung cancer. Naxitamab stimulates antibody-dependent cell-mediated cytotoxicity (ADCC) against GD2-expressing tumour cells.
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